In 1967, Miller Fisher described a pattern of ophthalmoplegia in patients with various pontine lesions, known as "one-and-a-half syndrome" (OAHS). In this syndrome, patients present with a combination of an ipsilateral conjugate horizontal gaze palsy (referring to the 'one' horizontal gaze palsy) and an ipsilateral internuclear ophthalmoplegia (INO) (referring to the 'half' of a
Internuclear Ophthalmoplegia. Internuclear ophthalmoplegia is characterized by paresis of ipsilateral eye adduction in horizontal gaze but not in convergence. It can be unilateral or bilateral. (See also Overview of Neuro-ophthalmologic and Cranial Nerve Disorders .) During horizontal gaze, the medial longitudinal fasciculus (MLF) on each side
Introduction. The association of internuclear ophthalmoplegia (INO) with exotropia in the contralateral eye was first described and termed as non-paralytic pontine exotropia (NPPE) by Bogousslavsky and Regli in 1983. 1 There has been a scarcity of reported cases documenting NPPE as a primary manifestation of vertebrobasilar stroke; most of them were reported in the 1990s. 2 NPPE is considered
Infrared oculography is a noninvasive, objective, and quantitative tool to assess an INO, which recently has become more widely available. Earlier studies have established the versional dysconjugacy index (VDI) 2 as a sensitive way to describe an INO. 3,4 However, the few studies that investigated VDI parameters in patients with MS had important limitations, such as small sample sizes and
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1Fr21.